Following a complaint from the Italian Fashion Giant Versace, police charged 110 people in southern California and Arizona in 2003 for selling fake Versace goods.
The award is the highest ever given to an Italian company defending its brand upto $20 Million (£13.4m), Versace says.
More than 70 retail shops were seized during the case.
"We have won a historic judgement," Versace's chief executive, Gian Giacomo Ferraris, was quoted as saying by the AFP news agency.
The effects of the ruling would benefit all of the luxury Italian brands, he added.
Versace had revenues of $359.6m (£241m) in 2009, according to Reuters.
But the company cut a quarter of its workforce last year, blaming a slump in demand for luxury goods and designer items.
The brother of the late Gianni Versace, Santo Versace was a key witness in the case, Reuters adds.
Brands loose major chunk of their earnings to fakes bring created in their name .. A step initiated by Versace should be taken by brands worldwide to ensure originality and authenticity ..